Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497762 | 0.88 | TACR1 (0.67) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5491515 | 0.87 | TACR1 (0.69) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5497810 | 0.86 | TACR1 (0.74) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5493710 | 0.83 | TACR1 (0.71) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5497890 | 0.82 | TACR1 (0.70) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5496528 | 0.82 | TACR1 (0.69) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5494072 | 0.80 | TACR1 (0.66) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5498842 | 0.80 | TACR1 (0.66) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5498839 | 0.79 | TACR1 (0.69) | TACR1CYP3A4SIGMAR1 | |
| SCHEMBL5498860 | 0.79 | TACR1 (0.63) | TACR1CYP3A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513814-A4 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO (JP) | 2007-03-14 | — | — | EP | disclosed |
| EP-1513814-A1 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099787-A1 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2003-12-04 | — | — | WO | disclosed |