Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488129 | 1.00 | AURKA (0.76) | AURKAAURKB | |
| SCHEMBL5494008 | 0.94 | AURKA (0.86) | AURKAAURKB | |
| SCHEMBL5497471 | 0.93 | AURKA (0.77) | AURKAAURKB | |
| SCHEMBL5488137 | 0.93 | AURKA (0.77) | AURKAAURKB | |
| SCHEMBL3489014 | 0.92 | AURKA (0.88) | AURKAAURKB | |
| SCHEMBL3489312 | 0.92 | AURKA (0.88) | AURKAAURKB | |
| SCHEMBL3491070 | 0.90 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL3488653 | 0.90 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL3491074 | 0.89 | AURKA (0.72) | AURKAAURKB | |
| SCHEMBL6527114 | 0.89 | AURKA (0.75) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578755-B1 | PHOSPHONOOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | EP | claimed |