Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163791 | 0.90 | AR (0.64) | ARSLC6A4SLC6A3KCNH2SLC6A2 | |
| SCHEMBL4179861 | 0.83 | AR (0.64) | ARSLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL4178705 | 0.80 | AR (0.68) | ARSLC6A4SLC6A3KCNH2SLC6A2 | |
| SCHEMBL4181001 | 0.76 | AR (0.73) | ARSLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL4168825 | 0.76 | AR (1.00) | ARSLC6A4SLC6A3KCNH2SLC6A2 | |
| SCHEMBL4181543 | 0.73 | AR (0.73) | ARSLC6A4SLC6A3KCNH2HTR2A | |
| SCHEMBL4179847 | 0.72 | AR (0.68) | ARSLC6A4SLC6A3KCNH2SLC6A2 | |
| SCHEMBL5503503 | 0.72 | AR (0.56) | ARSLC6A4SLC6A3KCNH2SLC6A2 | |
| SCHEMBL25451306 | 0.71 | AR (0.60) | ARSLC6A4SLC6A3KCNH2SLC6A2 | |
| SCHEMBL18164415 | 0.71 | SLC6A4 (0.49) | ARSLC6A4SLC6A3SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | claimed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | claimed |