Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.54 |
| ▸ | FABP7 | O15540 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497609 | 0.93 | KMT2A (0.59) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL31378081 | 0.93 | KMT2A (0.59) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL7262938 | 0.93 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL3623157 | 0.93 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL31419530 | 0.92 | KMT2A (0.49) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL10261416 | 0.91 | KMT2A (0.55) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL14759878 | 0.91 | KMT2A (0.60) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL7036852 | 0.91 | KMT2A (0.58) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL47693 | 0.90 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL7263679 | 0.90 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262169-B1 | Process for preparing peptide intermediates | MERCK & CO., INC. (US) | 2007-08-28 | — | — | US | disclosed |
| EP-1226158-B1 | PROCESS FOR PREPARING PEPTIDE INTERMEDIATES | MERCK SHARP & DOHME (GB) | 2003-07-02 | — | — | EP | disclosed |
| EP-1226158-A1 | PROCESS FOR PREPARING PEPTIDE INTERMEDIATES | MERCK SHARP & DOHME LTD. (GB) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001029065-A1 | PROCESS FOR PREPARING PEPTIDE INTERMEDIATES | MERCK SHARP & DOHME LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |