SCHEMBL5497852

SCHEMBL5497852

NC(=O)NCCC[C@@H](NC(N)=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
C3AR1 Q16581 1/20 0.55
SHMT1 P34896 1/20 0.44
FOLH1 Q04609 7/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
GNPAT O15228 1/20 0.41
MEN1 O00255 1/20 0.41
KLK7 P49862 1/20 0.41
KMT2A Q03164 1/20 0.41
NOD1 Q9Y239 3/20 0.40
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38
POLB P06746 1/20 0.38
TGFBR1 P36897 1/20 0.37
EPHX2 P34913 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5497855 1.00 C3AR1 (0.55) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL8071296 0.94 FOLH1 (0.50) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL12461742 0.94 FOLH1 (0.50) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL1765043 0.87 C3AR1 (0.45) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL1765039 0.87 C3AR1 (0.45) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL468877 0.87 FOLH1 (0.51) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL468875 0.87 FOLH1 (0.51) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL5490001 0.87 C3AR1 (0.45) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL27860339 0.86 C3AR1 (0.56) C3AR1SHMT1FOLH1CTDSP1GNPAT
SCHEMBL2113661 0.86 C3AR1 (0.56) C3AR1SHMT1FOLH1CTDSP1GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1616945-B1 Process for producing D-N-carbamoyl-alpha-amino acids KANEGAFUCHI CHEMICAL IND (JP) 2007-11-21 EP disclosed
EP-0801131-B1 PROCESS FOR PRODUCING D-N-CARBAMOYL-ALPHA-AMINO ACID KANEGAFUCHI CHEMICAL IND (JP) 2007-02-21 EP disclosed
EP-1616945-A1 Process for producing D-N-carbamoyl-alpha-amino acids KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-01-18 EP disclosed
EP-1616946-A1 Process for producing D-N-carbamoyl-alpha-amino acids KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-01-18 EP disclosed
EP-0801131-A1 PROCESS FOR PRODUCING D-N-CARBAMOYL-$g(a)-AMINO ACID Kanegafuchi Chemical Industry Co., Ltd. (JP) 1997-10-15 EP disclosed