Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1672847 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL905740 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL15916954 | 0.92 | — | — | |
| SCHEMBL239012 | 0.91 | — | — | |
| Water SCHEMBL5381081 | 0.87 | — | — | |
| Bromide SCHEMBL4656309 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL4474978 | 0.78 | — | — | |
| Bromide SCHEMBL27986213 | 0.75 | — | — | |
| SCHEMBL1978899 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL10449335 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429731-B1 | NANOPARTICULATE INSULIN FORMULATIONS | ELAN PHARMA INT LTD (IE) | 2007-01-03 | — | — | EP | claimed |
| US-10954345-B2 | Method of preparing monodispersed polymer polyols | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2021-03-23 | — | — | US | disclosed |
| US-10525422-B2 | Method of preparing thin film composite forward osmosis membranes using polyethylene porous supports | Korea University Research and Business Development (KR) | 2020-01-07 | — | — | US | disclosed |
| US-20190270853-A1 | METHOD OF PREPARING MONODISPERSED POLYMER POLYOLS | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2019-09-05 | — | — | US | disclosed |
| US-20180008939-A1 | METHOD OF PREPARING THIN FILM COMPOSITE FORWARD OSMOSIS MEMBRANES USING POLYETHYLENE POROUS SUPPORTS | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2018-01-11 | — | — | US | disclosed |
| EP-3199232-A1 | HOLLOW METAL NANOPARTICLE, CATALYST INCLUDING SAME, AND METHOD FOR MANUFACTURING HOLLOW METAL NANOPARTICLE | LG Chem, Ltd. (KR) | 2017-08-02 | — | — | EP | disclosed |
| US-20140220640-A1 | METHOD FOR MANUFACTURING DETOXIFICATED LIGNOCELLULOSIC BIOMASS HYDROLYSATE WITH DECREASED OR ELIMINATED TOXICITY AND METHOD FOR MANUFACTURING ORGANIC OR AND BIOFUEL USING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-07 | — | — | US | disclosed |