Styrene

Styrene

SCHEMBL5498948

C=Cc1ccccc1.CC(=CCCN(C)C)C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.45
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
BCHE P06276 4/20 0.36
ACHE P22303 4/20 0.36
HTT P42858 2/20 0.36
BCL2L1 Q07817 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
GP6 Q9HCN6 1/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC6 Q9UBN7 1/20 0.34
GLA P06280 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
OPRM1 P35372 2/20 0.34
DRD3 P35462 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7258485 0.87 BCHE (0.35) AKR1C3BCHEHTTBCL2L1KDM4E
Styrene SCHEMBL4854249 0.86 AKR1C3 (0.42) AKR1C3ALDH1A1TSHRBCHEACHE
Styrene SCHEMBL5662638 0.83 AKR1C3 (0.49) AKR1C3ALDH1A1TSHRHTTMEN1
Styrene SCHEMBL5725939 0.83 AKR1C3 (0.49) AKR1C3ALDH1A1TSHRHTTMEN1
Styrene SCHEMBL5665139 0.83 AKR1C3 (0.49) AKR1C3ALDH1A1TSHRHTTMEN1
SCHEMBL6352251 0.81 CHRM2 (0.41) ALDH1A1TSHRCYP3A4CYP2D6KDM4E
Styrene SCHEMBL10409330 0.81 BCHE (0.38) AKR1C3ALDH1A1TSHRBCHEACHE
Styrene SCHEMBL3441339 0.81 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTMEN1
Styrene SCHEMBL3141180 0.81 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTMEN1
Styrene SCHEMBL393960 0.81 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980028-B1 Erasable image forming material TOSHIBA KK (JP) 2007-11-28 EP disclosed
US-6203603-B1 COLOR FORMER, DEVELOPER, MATRIX AND POLYMER DECOLORIZER KABUSHIKI KAISHA TOSHIBA (JP) 2001-03-20 US disclosed
EP-0980028-A1 Erasable image forming material KABUSHIKI KAISHA TOSHIBA (JP) 2000-02-16 EP disclosed
US-5180637-A Heat and moisture resistant SAKURA COLOR PRODUCTS CORPORATION (JP) 1993-01-19 US disclosed