Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121027 | 0.89 | PTGDR2 (0.59) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5106685 | 0.89 | PTGDR2 (0.62) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5120700 | 0.88 | PTGDR2 (0.57) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5499474 | 0.87 | PTGDR2 (0.58) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5113997 | 0.86 | PTGDR2 (0.58) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5122099 | 0.85 | PTGDR2 (0.40) | PTGDR2MEN1KMT2APOLB | |
| SCHEMBL5120902 | 0.85 | PTGDR2 (0.61) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5111077 | 0.80 | PTGDR2 (0.53) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5121162 | 0.78 | PTGDR2 (0.64) | PTGDR2MEN1KMT2APOLBPDPK1 | |
| SCHEMBL5106826 | 0.77 | PTGDR2 (0.68) | PTGDR2MEN1KMT2APDPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784182-A1 | 2-SULFANYL-BENZIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021418-A1 | 2-SULFANYL-BENZOIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-02 | — | — | WO | disclosed |