Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32685228 | 0.83 | TSHR (0.41) | TSHRTP53TDP1ALDH1A1CA1 | |
| SCHEMBL7344387 | 0.79 | TSHR (0.44) | TSHRTP53TDP1ALDH1A1CA1 | |
| SCHEMBL7148720 | 0.75 | MPI (0.32) | — | |
| SCHEMBL28394231 | 0.73 | — | — | |
| SCHEMBL7990296 | 0.73 | TSHR (0.36) | TSHRTP53TDP1ALDH1A1 | |
| SCHEMBL21114488 | 0.71 | — | — | |
| SCHEMBL965530 | 0.71 | — | — | |
| SCHEMBL7169460 | 0.71 | — | — | |
| SCHEMBL29557438 | 0.71 | — | — | |
| SCHEMBL946153 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1770109-B1 | Process of preparing polyamine-epihalohydrin resins with reduced byproduct content | HERCULES INC (US) | 2012-08-08 | — | — | EP | disclosed |
| EP-1777247-A2 | Reduced byproduct polyamidoamine-epihalohydrin resins | HERCULES INCORPORATED (US) | 2007-04-25 | — | — | EP | disclosed |