Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.58 |
| ▸ | GLP1R | P43220 | 5/20 | 0.53 |
| ▸ | SCTR | P47872 | 1/20 | 0.53 |
| ▸ | TFPI | P10646 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 6/20 | 0.51 |
| ▸ | NPY1R | P25929 | 5/20 | 0.51 |
| ▸ | NPY2R | P49146 | 4/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500020 | 1.00 | C5AR1 (0.58) | C5AR1GLP1RSCTRTFPINPY4R | |
| SCHEMBL29716050 | 0.94 | GLP1R (0.62) | C5AR1GLP1RSCTRTFPIGCGR | |
| SCHEMBL30512627 | 0.90 | TFPI (0.64) | C5AR1GLP1RSCTRTFPIMC4R | |
| SCHEMBL31680257 | 0.90 | C5AR1 (0.58) | C5AR1GLP1RSCTRTFPINPY4R | |
| SCHEMBL30567797 | 0.90 | TFPI (0.62) | TFPINPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30307617 | 0.89 | GLP1R (0.64) | GLP1RSCTRTFPIGCGR | |
| SCHEMBL30424730 | 0.88 | C5AR1 (0.53) | C5AR1GLP1RSCTRTFPINPY4R | |
| SCHEMBL30974468 | 0.88 | NPY4R (0.53) | C5AR1GLP1RSCTRNPY4RNPY1R | |
| SCHEMBL29871041 | 0.88 | GLP1R (0.59) | C5AR1GLP1RSCTRTFPIGCGR | |
| SCHEMBL29904562 | 0.87 | C5AR1 (0.55) | C5AR1GLP1RSCTRNPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635629-A4 | PLANT TRANSCRIPTIONAL REGULATORS OF DISEASE RESISTANCE | MENDEL BIOTECHNOLOGY INC (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1635629-A2 | PLANT TRANSCRIPTIONAL REGULATORS OF DISEASE RESISTANCE | Mendel Biotechnology, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108900-A2 | PLANT TRANSCRIPTIONAL REGULATORS OF DISEASE RESISTANCE | MENDEL BIOTECHNOLOGY, INC. (US) | 2004-12-16 | — | — | WO | disclosed |