Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285959 | 0.83 | ADORA2A (0.73) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL5493995 | 0.74 | ADORA2A (0.54) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL4287838 | 0.73 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BRAB9ANPC1 | |
| SCHEMBL18969623 | 0.73 | ADORA2A (0.67) | ADORA2AADORA1MEN1KMT2AADORA2B | |
| SCHEMBL3194666 | 0.72 | ADORA2A (0.75) | ADORA2AADORA1ADORA2BRAB9ANPC1 | |
| SCHEMBL4292883 | 0.72 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BRAB9ANPC1 | |
| SCHEMBL4293175 | 0.71 | ADORA2A (0.83) | ADORA2AADORA1ADORA2BRAB9ANPC1 | |
| SCHEMBL4299463 | 0.71 | ADORA2A (0.80) | ADORA2AADORA1ADORA2BRAB9ANPC1 | |
| SCHEMBL27643438 | 0.71 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BMAPT | |
| SCHEMBL4288709 | 0.71 | ADORA2A (0.78) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682129-B1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-02-21 | — | — | EP | claimed |