Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504082 | 0.70 | CASR (0.39) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9913300 | 0.69 | HPGD (0.40) | HPGDNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL5503937 | 0.66 | HPGD (0.36) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6009956 | 0.66 | HPGD (0.36) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3640956 | 0.63 | ACACB (0.54) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5503668 | 0.62 | CASR (0.39) | HPGDNPC1RAB9ASMN1; SMN2GHSR | |
| SCHEMBL15261415 | 0.60 | HPGD (0.57) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14047948 | 0.59 | ESR1 (0.44) | HPGDNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL19669538 | 0.59 | IDO1 (0.44) | HPGDTSHRKMT2ATDP1 | |
| SCHEMBL295944 | 0.59 | ESR1 (0.44) | HPGDNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828111-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059252-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-06-08 | — | — | WO | disclosed |