Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500652 | 0.77 | CA1 (0.41) | TRPV1 | |
| SCHEMBL2946620 | 0.75 | ADRB3 (0.40) | TRPV1 | |
| SCHEMBL2948935 | 0.71 | CA1 (0.43) | TRPV1 | |
| SCHEMBL5505542 | 0.67 | — | — | |
| SCHEMBL5282552 | 0.65 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL2959317 | 0.64 | KDM4E (0.44) | — | |
| SCHEMBL3386124 | 0.64 | SLC7A5 (0.45) | TRPV1 | |
| SCHEMBL2957634 | 0.63 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL13238790 | 0.63 | TRPV1 (0.37) | TRPV1 | |
| SCHEMBL2955086 | 0.63 | TRPV1 (0.61) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861357-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006101318-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-28 | — | — | WO | disclosed |