Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217558 | 0.85 | TARBP2 (0.49) | TARBP2PPARGPPARANPC1RAB9A | |
| SCHEMBL3579118 | 0.81 | TARBP2 (0.50) | TARBP2PPARGPPARANPC1RAB9A | |
| SCHEMBL5093853 | 0.75 | TARBP2 (0.54) | TARBP2PPARGPPARANPC1RAB9A | |
| SCHEMBL1981068 | 0.73 | PPARG (0.54) | TARBP2PPARGPPARANPC1RAB9A | |
| SCHEMBL4482083 | 0.72 | TARBP2 (0.39) | TARBP2NPC1RAB9ARXFP1KDM4E | |
| SCHEMBL5216035 | 0.72 | TARBP2 (0.54) | TARBP2PPARGPPARANPC1RAB9A | |
| SCHEMBL1557048 | 0.72 | TARBP2 (0.53) | TARBP2PPARGPPARANPC1RAB9A | |
| SCHEMBL3996100 | 0.72 | TARBP2 (0.50) | TARBP2PPARGPPARANPC1RAB9A | |
| SCHEMBL4473360 | 0.72 | TARBP2 (0.41) | TARBP2NPC1RAB9ARXFP1KDM4E | |
| Ethane SCHEMBL28752838 | 0.71 | TARBP2 (0.52) | TARBP2PPARGPPARANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786790-A1 | OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006019833-A1 | OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |