Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.64 |
| ▸ | ABL1 | P00519 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194354 | 0.87 | AOC3 (0.69) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3941639 | 0.84 | AOC3 (0.67) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| SCHEMBL14365394 | 0.82 | AOC3 (0.62) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| SCHEMBL3942963 | 0.82 | AOC3 (0.67) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3940786 | 0.81 | AOC3 (0.63) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| SCHEMBL3943224 | 0.81 | AOC3 (0.60) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6242808 | 0.81 | AOC3 (0.72) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| Carbamic Acid SCHEMBL3936321 | 0.80 | AOC3 (0.62) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4864960 | 0.79 | AOC3 (0.73) | AOC3ABL1MEN1KMT2AALDH1A1 | |
| Carbamic Acid SCHEMBL6441307 | 0.79 | AOC3 (0.64) | AOC3ABL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006011631-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-02-02 | — | — | WO | disclosed |