Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 4/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318390 | 1.00 | GABRR1 (0.35) | GABRR1GABRR2DPP7CPN1CPB2 | |
| SCHEMBL3033289 | 1.00 | GABRR1 (0.35) | GABRR1GABRR2DPP7CPN1CPB2 | |
| SCHEMBL3276769 | 1.00 | GABRR1 (0.35) | GABRR1GABRR2DPP7CPN1CPB2 | |
| SCHEMBL3031676 | 1.00 | GABRR1 (0.35) | GABRR1GABRR2DPP7CPN1CPB2 | |
| SCHEMBL3033285 | 1.00 | GABRR1 (0.35) | GABRR1GABRR2DPP7CPN1CPB2 | |
| SCHEMBL3031679 | 1.00 | GABRR1 (0.35) | GABRR1GABRR2DPP7CPN1CPB2 | |
| SCHEMBL16977621 | 0.84 | EPHX2 (0.34) | DPP7GAADPP4 | |
| SCHEMBL3025369 | 0.83 | CYP46A1 (0.34) | GAACYP46A1 | |
| SCHEMBL3025364 | 0.83 | CYP46A1 (0.34) | GAACYP46A1 | |
| SCHEMBL1314601 | 0.83 | CYP46A1 (0.34) | GAACYP46A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641784-B1 | 4-(AMINOMETHYL)-PIPERIDINE BENZAMIDES AS 5HT4 -ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2007-06-13 | — | — | EP | disclosed |