Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4117760 | 1.00 | PTGDR2 (0.67) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4118694 | 0.95 | PTGDR2 (0.69) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4124205 | 0.91 | PTGDR2 (0.73) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4114779 | 0.91 | PTGDR2 (0.55) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4135150 | 0.91 | PTGDR2 (0.65) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4122705 | 0.90 | PTGDR2 (0.73) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4117897 | 0.89 | PTGDR2 (0.67) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4124905 | 0.89 | PTGDR2 (0.59) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4129787 | 0.89 | PTGDR2 (0.66) | PTGDR2MEN1KMT2ALMNAPOLB | |
| SCHEMBL4129788 | 0.89 | PTGDR2 (0.66) | PTGDR2MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740547-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100321-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |