Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188133 | 0.89 | AR (0.62) | ARSLC22A12HTR2ASLC6A4KCNH2 | |
| SCHEMBL4171619 | 0.84 | AR (0.67) | ARSLC22A12ESRRAMAPTHPGD | |
| SCHEMBL26193516 | 0.81 | AR (0.55) | ARHPGDHTR2ASLC6A4KCNH2 | |
| SCHEMBL4181860 | 0.79 | AR (0.67) | ARSLC22A12ESRRAPGR | |
| SCHEMBL4179840 | 0.79 | AR (0.69) | ARSLC22A12ESRRAMAPTRAB9A | |
| SCHEMBL4178023 | 0.78 | AR (0.74) | ARSLC22A12ESRRAL3MBTL1PGR | |
| SCHEMBL4188116 | 0.77 | AR (0.68) | ARSLC22A12HTR2ASLC6A4KCNH2 | |
| SCHEMBL4171318 | 0.75 | AR (0.58) | ARSLC22A12HTR2ASLC6A4KCNH2 | |
| SCHEMBL4178475 | 0.75 | AR (0.68) | ARSLC22A12L3MBTL1HTR2ASLC6A4 | |
| SCHEMBL4182051 | 0.74 | AR (0.59) | ARSLC22A12ESRRAHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | claimed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | claimed |