Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | CCR1 | P32246 | 3/20 | 0.56 |
| ▸ | CCR5 | P51681 | 3/20 | 0.56 |
| ▸ | CCR8 | P51685 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | METAP1 | P53582 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28331391 | 0.85 | GRM5 (0.62) | GRM5KDM4ECCR1CCR5CCR8 | |
| SCHEMBL28936052 | 0.84 | CYP2A6 (0.54) | GRM5KDM4ECCR1CCR5CCR8 | |
| SCHEMBL858806 | 0.83 | KDM4E (0.72) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL25462779 | 0.82 | GRM5 (0.48) | GRM5KDM4ECCR1CCR5CCR8 | |
| SCHEMBL11064947 | 0.82 | IDO1 (0.51) | GRM5KDM4ECCR1CCR5CCR8 | |
| SCHEMBL31558882 | 0.82 | KDM4E (0.56) | GRM5KDM4ECCR1CCR5CCR8 | |
| SCHEMBL29652637 | 0.81 | GRM5 (0.46) | GRM5KDM4ECCR1CCR5CCR8 | |
| SCHEMBL12853986 | 0.80 | KDM4E (0.68) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL12853975 | 0.80 | KDM4E (0.68) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL22881677 | 0.80 | KDM4E (0.68) | KDM4ECCR1CCR5CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343998-B2 | Synthetic path to pharmaceutically acceptable Vismodegib | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2019-07-09 | — | — | US | claimed |
| EP-3381900-A1 | NEW SYNTHETIC PATH TO PHARMACEUTICALLY ACCEPTABLE VISMODEGIB | AZAD Pharmaceutical Ingredients AG (CH) | 2018-10-03 | — | — | EP | claimed |
| US-20180273477-A1 | Synthetic Path To Pharmaceutically Acceptable Vismodegib | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2018-09-27 | — | — | US | claimed |
| US-8110642-B2 | Synthesis of vinylphenylpyridine and living anionic polymerization | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-02-07 | — | — | US | claimed |
| CN-118284339-A | Antiviral agent, antiviral product and antiviral treatment liquid | 共同印刷株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-115558392-B | Aluminum frame mirror and assembly process | 江苏通达家居用品有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117082976-A | Stable emulsions | 安道麦阿甘有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-109912603-B | Practical method for synthesizing novel bioactive molecules by using N-methoxyamide as nitrogen source | 苏州大学 | 2021-08-03 | — | — | CN | disclosed |
| EP-3227018-B1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | UNIV VIRGINIA COMMONWEALTH (US) | 2021-06-30 | — | — | EP | disclosed |
| EP-3227018-B1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | UNIV VIRGINIA COMMONWEALTH (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-03-19 | — | — | US | disclosed |
| WO-2001010395-A1 | USE OF SYNTHETIC POLYMERS | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2001-02-15 | — | — | WO | disclosed |
| CN-1046218-C | Process for the carbonylation of acetylenically unsaturated compounds | SHELL INT RESEARCH (NL) | 1999-11-10 | — | — | CN | disclosed |
| CN-1088851-A | The catalyst system that the carbonylation of acetylenically unsaturated compound is used | SHELL INT RESEARCH (NL) | 1994-07-06 | — | — | CN | disclosed |
| US-4727148-A | Certain aromatization process for preparing 1-alkyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinoline carboxylic acid | ETHYL CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4649202-A | Brominative aromatization of 4-cyclohexenylpyridines | ETHYL CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4604467-A | Certain 4-(3,4-dibromocyclohexyl)pyridines | ETHYL CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| US-4135045-A | PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4048415-A | TITANIUM-ALUMINUM COORDINATION CATALYSTS | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | PAH, DBH, AHR | GRM5 4493/4885KDM4E 357/4885CCR1 555/4885 |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | PAH, DBH, AHR | GRM5 4493/4885KDM4E 357/4885CCR1 555/4885 |
| US-10343998-B2 | Synthetic path to pharmaceutically acceptable Vismodegib | EGFR, SMO, ERBB2 | GRM5 1444/4885KDM4E 3915/4885CCR1 1186/4885 |
| US-20180273477-A1 | Synthetic Path To Pharmaceutically Acceptable Vismodegib | EGFR, SMO, ERBB2 | GRM5 1444/4885KDM4E 3915/4885CCR1 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.