Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 20/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 10/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499241 | 0.87 | CACNA1B (0.49) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL5504326 | 0.86 | CACNA1B (0.48) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL4283326 | 0.86 | CACNA1B (0.67) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL4282316 | 0.86 | CACNA1B (0.67) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL3961603 | 0.77 | CACNA1B (0.54) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL4278395 | 0.77 | CACNA1B (0.67) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL4278393 | 0.77 | CACNA1B (0.67) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL4278375 | 0.75 | CACNA1B (0.59) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL4283315 | 0.75 | CACNA1B (0.61) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL4283313 | 0.75 | CACNA1B (0.61) | CACNA1BNR1I2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814851-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006040181-A2 | 4-PHENYLSULFONAMIDOPIPERIDINES AS CALCIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2006-04-20 | — | — | WO | disclosed |