Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678845 | 0.85 | F10 (0.58) | F10 | |
| SCHEMBL1031643 | 0.85 | F10 (0.58) | F10 | |
| SCHEMBL1031085 | 0.85 | F10 (0.58) | F10 | |
| SCHEMBL1031001 | 0.85 | F10 (0.52) | F10KDM4E | |
| SCHEMBL1028208 | 0.85 | F10 (0.52) | F10KDM4E | |
| SCHEMBL1029786 | 0.79 | F10 (0.57) | F10 | |
| SCHEMBL8262142 | 0.79 | F10 (0.57) | F10 | |
| SCHEMBL1027001 | 0.78 | F10 (0.58) | F10 | |
| SCHEMBL1028426 | 0.78 | F10 (0.58) | F10 | |
| SCHEMBL8261736 | 0.78 | F10 (0.58) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814855-A2 | DICARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006048152-A2 | DICARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-11 | — | — | WO | disclosed |