Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418997 | 0.85 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1SLC7A5TP53 | |
| SCHEMBL12325970 | 0.84 | SLC1A1 (0.46) | SLC1A3SLC1A2SLC1A1GABRR1ADRA1A | |
| SCHEMBL29950790 | 0.83 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1GABRR1SLC7A5 | |
| SCHEMBL1058202 | 0.83 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1GABRR1SLC7A5 | |
| SCHEMBL4738612 | 0.83 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1GABRR1SLC7A5 | |
| Ammonia Solution, Strong SCHEMBL8998227 | 0.82 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5TP53 | |
| Hydrochloric Acid SCHEMBL17653157 | 0.81 | SLC1A3 (0.59) | SLC1A3SLC1A2SLC1A1GABRR1SLC7A5 | |
| SCHEMBL10618415 | 0.80 | GABRR1 (0.44) | SLC1A3SLC1A2SLC1A1GABRR1ADRA1A | |
| SCHEMBL20702135 | 0.78 | SLC1A3 (0.58) | SLC1A3SLC1A2SLC1A1TP53ADRA1A | |
| SCHEMBL3992147 | 0.77 | SLC1A2 (0.47) | SLC1A3SLC1A2SLC1A1GABRR1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539183-A4 | THERAPEUTIC TREATMENT METHODS | HOLLIS EDEN PHARMACEUTICALS (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1628685-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2006-03-01 | — | — | EP | disclosed |
| EP-1539183-A1 | THERAPEUTIC TREATMENT METHODS | Hollis-Eden Pharmaceuticals Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004096286-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| WO-2004019953-A1 | THERAPEUTIC TREATMENT METHODS | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2004-03-11 | — | — | WO | disclosed |