Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.78 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29817411 | 0.93 | ESR1 (0.64) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL3889569 | 0.93 | ESR1 (0.64) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL3890967 | 0.88 | ESR1 (1.00) | ESR1ESR2MAPTCNR1CNR2 | |
| SCHEMBL4030022 | 0.84 | ESR1 (0.75) | ESR1ESR2KDM4ECRHR1 | |
| SCHEMBL4032053 | 0.81 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL4029130 | 0.80 | ESR1 (0.46) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL4027158 | 0.79 | ESR1 (0.45) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL4034557 | 0.79 | ESR1 (0.44) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL4031240 | 0.78 | ESR1 (0.58) | ESR1ESR2MAPTKDM4EALDH1A1 | |
| SCHEMBL4032697 | 0.77 | ESR1 (0.43) | ESR1ESR2CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856151-A2 | ESTROGEN RECEPTOR STRUCTURE | Wyeth (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006078733-A2 | ESTROGEN RECEPTOR STRUCTURE | WYETH (US) | 2006-07-27 | — | — | WO | disclosed |