SCHEMBL5502007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5498157	0.84	TAAR1 (0.52)	TAAR1HTR2AHTR2CADRA1A
	SCHEMBL31455925	0.83	HTR2A (0.74)	TAAR1HTR2AHTR2CADRA1AHTR2B
	SCHEMBL5501939	0.83	TAAR1 (0.50)	TAAR1HTR2AHTR2CADRA1A
	SCHEMBL5502000	0.82	SLC6A4 (0.48)	HTR2AHTR2C
	SCHEMBL5501642	0.78	TAAR1 (0.51)	TAAR1HTR2AHTR2CADRA1AHTR2B
	SCHEMBL5501246	0.77	TAAR1 (0.50)	TAAR1HTR2AADRA1A
	Hydrochloric Acid SCHEMBL5457539	0.77	TAAR1 (0.50)	TAAR1HTR2AHTR2CADRA1AHTR2B
	SCHEMBL3062955	0.73	TAAR1 (0.69)	TAAR1HTR2AADRA1A
	SCHEMBL5504223	0.73	TAAR1 (0.44)	TAAR1HTR2AADRA1A
	SCHEMBL5809547	0.70	HTR2A (1.00)	TAAR1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.