Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188231 | 0.91 | AR (0.65) | ARSLC22A12PLA2G7KDM4EMEN1 | |
| SCHEMBL4178134 | 0.91 | AR (0.65) | ARSLC22A12PGRESRRA | |
| SCHEMBL4163780 | 0.81 | AR (0.72) | ARSLC22A12SLC6A4PGRESRRA | |
| SCHEMBL4181443 | 0.74 | AR (0.72) | ARSLC22A12SLC6A4KDM4EMEN1 | |
| SCHEMBL4168834 | 0.73 | AR (0.72) | ARSLC22A12SLC6A4PGRESRRA | |
| SCHEMBL17052853 | 0.72 | AR (0.65) | ARSLC22A12SLC6A4PLA2G7PGR | |
| SCHEMBL923687 | 0.72 | AR (0.49) | ARSLC6A4 | |
| SCHEMBL4175953 | 0.72 | AR (1.00) | ARSLC22A12PGR | |
| SCHEMBL4181860 | 0.71 | AR (0.67) | ARSLC22A12PGRESRRA | |
| SCHEMBL4171619 | 0.71 | AR (0.67) | ARSLC22A12MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |