Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | ITK | Q08881 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945978 | 0.96 | ADORA1 (0.47) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| Hydrochloric Acid SCHEMBL948352 | 0.95 | ADORA1 (0.47) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| SCHEMBL945760 | 0.90 | ADORA1 (0.56) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| Hydrochloric Acid SCHEMBL945957 | 0.90 | ADORA1 (0.45) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| SCHEMBL3737757 | 0.90 | ADORA1 (0.45) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| Hydrochloric Acid SCHEMBL946972 | 0.89 | ADORA1 (0.55) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| SCHEMBL946228 | 0.88 | ADORA1 (0.45) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| Hydrochloric Acid SCHEMBL946906 | 0.87 | ADORA1 (0.45) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| SCHEMBL950112 | 0.84 | ADORA1 (0.46) | ADORA1ADORA2AADORA3ADORA2BIKBKB | |
| SCHEMBL3743152 | 0.83 | ADORA1 (0.45) | ADORA1ADORA2AADORA3ADORA2BIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740574-B1 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2007-06-27 | — | — | EP | claimed |