Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8360319 | 0.86 | TP53 (0.39) | POLBALDH1A1 | |
| SCHEMBL30337061 | 0.85 | POLB (0.47) | POLBNR1H4NPSR1RXRARXRB | |
| SCHEMBL55627 | 0.85 | POLB (0.47) | POLBNR1H4NPSR1RXRARXRB | |
| Methane SCHEMBL9285119 | 0.84 | POLB (0.46) | POLBNR1H4NPSR1RXRARXRB | |
| SCHEMBL28591591 | 0.83 | POLB (0.45) | POLBNR1H4NPSR1RXRARXRB | |
| SCHEMBL7693390 | 0.79 | NR1H4 (0.48) | POLBNR1H4NPSR1RXRARXRB | |
| SCHEMBL6611287 | 0.76 | NPSR1 (0.49) | POLBNR1H4NPSR1RXRARXRB | |
| SCHEMBL2163934 | 0.76 | POLB (0.42) | POLBNR1H4NPSR1RXRARXRB | |
| SCHEMBL28093039 | 0.76 | POLB (0.42) | POLBNR1H4NPSR1RXRARXRB | |
| SCHEMBL7882529 | 0.76 | NR1H4 (0.43) | POLBNR1H4NPSR1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114614-A1 | PROCESS FOR THE PRODUCTION OF MODIFIED POLYETHYLENE MATERIALS WITH INHERENT ANTI-FOG PROPERTIES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-07-06 | — | — | WO | disclosed |
| EP-1833870-A1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | E.I.Du pont de nemours and company (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006066026-A1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20020040081-A1 | Blends of phosphites and antioxidants | DOVER CHEMICAL | 2002-04-04 | — | — | US | disclosed |