Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000614 | 0.90 | TRPV1 (0.56) | TRPV1 | |
| Methanesulfonamide SCHEMBL5503061 | 0.87 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL1998884 | 0.82 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL2000369 | 0.79 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL2003817 | 0.78 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL2952151 | 0.76 | EPHX2 (0.49) | TRPV1 | |
| SCHEMBL2948751 | 0.75 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL2006323 | 0.75 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL2004075 | 0.75 | — | — | |
| SCHEMBL2004076 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861358-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006101321-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-28 | — | — | WO | disclosed |