SCHEMBL5503133

SCHEMBL5503133

CCC(S)[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7223036 0.75
SCHEMBL7229293 0.75
SCHEMBL10638108 0.71
SCHEMBL1758111 0.69
SCHEMBL7224474 0.69
SCHEMBL7230094 0.69
SCHEMBL7224095 0.67
SCHEMBL7221879 0.67
SCHEMBL4257803 0.67
SCHEMBL2521834 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0966456-A4 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF RES FOUNDATION OF (US) 2000-07-26 EP claimed
EP-0966456-A1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-12-29 EP claimed
US-5811452-A ADMINISTERING WITH PACLITAXEL OR DOXORUBICIN THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-09-22 US claimed
WO-1998030553-A1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-07-16 WO claimed
US-4567200-A Esters of mercapto acyl-carnitines and pharmaceutical compositions containing same SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1986-01-28 US claimed
EP-0161007-A2 Retro - inverso C-Terminal hexapeptide analogues of substance P ENI-Ente Nazionale Idrocarburi (IT) 1985-11-13 EP claimed
US-11866648-B2 Process for producing polymerizable composition for optical materials MITSUI CHEMICALS, INC. (JP) 2024-01-09 US disclosed
US-11639413-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2023-05-02 US disclosed
US-20220162486-A1 PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME TOKUYAMA CORPORATION (JP) 2022-05-26 US disclosed
EP-3950624-A1 PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME Tokuyama Corporation (JP) 2022-02-09 EP disclosed
EP-3919584-A1 METHOD FOR PRODUCING POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2021-12-08 EP disclosed
CN-109790272-B Polymerizable composition for optical material and use thereof 三井化学株式会社 2021-11-19 CN disclosed
CN-113646281-A Photochromic optical article and method of making same 株式会社德山 2021-11-12 CN disclosed
EP-0966456-A4 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF RES FOUNDATION OF (US) 2000-07-26 EP disclosed
EP-0966456-A1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-12-29 EP disclosed
US-5811452-A ADMINISTERING WITH PACLITAXEL OR DOXORUBICIN THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-09-22 US disclosed
WO-1998030553-A1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-07-16 WO disclosed
US-4593043-A Mercapto acyl-carnitines and pharmaceutical compositions containing same SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1986-06-03 US disclosed
US-4567200-A Esters of mercapto acyl-carnitines and pharmaceutical compositions containing same SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1986-01-28 US disclosed
US-4510318-A DETOXIFICATION; BURN INJURIES; MUCOLYTIC AGENTS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1985-04-09 US disclosed