Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4123301 | 1.00 | PTGDR2 (0.59) | PTGDR2P2RY1LMNAGFERNPSR1 | |
| SCHEMBL4123305 | 1.00 | PTGDR2 (0.59) | PTGDR2P2RY1LMNAGFERNPSR1 | |
| SCHEMBL4115596 | 0.90 | PTGDR2 (0.60) | PTGDR2LMNAGFERNPSR1 | |
| SCHEMBL4115600 | 0.90 | PTGDR2 (0.60) | PTGDR2LMNAGFERNPSR1 | |
| SCHEMBL5501675 | 0.90 | PTGDR2 (0.60) | PTGDR2LMNAGFERNPSR1 | |
| SCHEMBL4124845 | 0.88 | PTGDR2 (0.58) | PTGDR2LMNAGFERNPSR1 | |
| SCHEMBL4124840 | 0.88 | PTGDR2 (0.58) | PTGDR2LMNAGFERNPSR1 | |
| SCHEMBL4124003 | 0.86 | PTGDR2 (0.51) | PTGDR2LMNAGFERNPSR1SMN1; SMN2 | |
| SCHEMBL4123997 | 0.86 | PTGDR2 (0.51) | PTGDR2LMNAGFERNPSR1SMN1; SMN2 | |
| SCHEMBL4128077 | 0.85 | PTGDR2 (0.54) | PTGDR2LMNAGFERNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740547-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100321-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |