Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 9/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6543814 | 0.99 | HDAC1 (0.43) | HDAC1NAMPTANPEPF7F2 | |
| SCHEMBL5497155 | 0.93 | MEN1 (0.40) | HDAC1F7F2F10CYP1A2 | |
| Hydrochloric Acid SCHEMBL6543212 | 0.92 | MEN1 (0.39) | HDAC1F7F2F10CYP1A2 | |
| SCHEMBL5499918 | 0.89 | ANPEP (0.41) | HDAC1ANPEPF7F2F10 | |
| SCHEMBL5499064 | 0.88 | POLB (0.44) | ANPEPF7F2F10CYP1A2 | |
| Hydrochloric Acid SCHEMBL6543837 | 0.88 | ANPEP (0.41) | HDAC1ANPEPF7F2F10 | |
| Hydrochloric Acid SCHEMBL6544314 | 0.87 | POLB (0.43) | ANPEPF7F2F10CYP1A2 | |
| SCHEMBL5498018 | 0.85 | F7 (0.46) | HDAC1NAMPTF7F2F10 | |
| Hydrochloric Acid SCHEMBL6543529 | 0.85 | F7 (0.46) | HDAC1NAMPTF7F2F10 | |
| SCHEMBL5497090 | 0.85 | F7 (0.43) | F7F2F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| EP-1453852-A2 | SELECTIVE UROKINASE INHIBITORS | Wilex AG (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003053999-A2 | SELECTIVE ARYLGUANIDINE PEPTIDES AS UROKINASE INHIBITORS | WILEX AG (DE) | 2003-07-03 | — | — | WO | disclosed |