Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.60 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471621 | 0.89 | F10 (0.55) | F10 | |
| SCHEMBL5208178 | 0.86 | F10 (0.60) | F10 | |
| SCHEMBL5445168 | 0.84 | F10 (0.63) | F10PTGS2 | |
| SCHEMBL5209703 | 0.84 | F10 (0.62) | F10 | |
| SCHEMBL5216384 | 0.83 | F10 (0.57) | F10 | |
| SCHEMBL5507036 | 0.83 | F10 (0.66) | F10 | |
| SCHEMBL4001644 | 0.82 | F10 (0.68) | F10PTGS2 | |
| SCHEMBL4001639 | 0.82 | F10 (0.68) | F10PTGS2 | |
| SCHEMBL5212744 | 0.82 | F10 (0.60) | F10PTGS2 | |
| SCHEMBL5509017 | 0.82 | F10 (0.56) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |