Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498727 | 0.87 | NR4A2 (0.39) | CTSACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5498610 | 0.87 | CYP1A2 (0.33) | CTSACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5505254 | 0.82 | ITGB1 (0.35) | CTSACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5499243 | 0.81 | CTSA (0.36) | CTSAALDH1A1HSP90AA1NPC1 | |
| SCHEMBL2286528 | 0.79 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6NFKB1PNMT | |
| SCHEMBL2283666 | 0.79 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2D6NFKB1PNMT | |
| SCHEMBL5502566 | 0.74 | NR4A2 (0.40) | CTSACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5498612 | 0.72 | HTT (0.35) | CYP1A2PNMTGAAALDH1A1NR4A2 | |
| SCHEMBL5501405 | 0.72 | NR4A2 (0.38) | CTSACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5502204 | 0.71 | MEN1 (0.31) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773124-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008159-A1 | A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE | BAYER CROPSCIENCE AG (DE) | 2006-01-26 | — | — | WO | disclosed |