Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505498 | 0.91 | PTGDR2 (0.64) | PTGDR2MEN1KMT2A | |
| SCHEMBL5111468 | 0.90 | PTGDR2 (0.62) | PTGDR2MEN1KMT2A | |
| SCHEMBL5120709 | 0.85 | PTGDR2 (0.71) | PTGDR2MEN1KMT2A | |
| SCHEMBL5500163 | 0.83 | PTGDR2 (0.60) | PTGDR2MEN1KMT2A | |
| SCHEMBL5112492 | 0.82 | PTGDR2 (0.39) | PTGDR2MEN1KMT2A | |
| SCHEMBL5122047 | 0.81 | PTGDR2 (0.70) | PTGDR2MEN1KMT2A | |
| SCHEMBL5113995 | 0.79 | PTGDR2 (0.70) | PTGDR2MEN1KMT2A | |
| SCHEMBL5111616 | 0.78 | PTGDR2 (0.73) | PTGDR2MEN1KMT2A | |
| SCHEMBL5120448 | 0.78 | PTGDR2 (0.74) | PTGDR2MEN1KMT2A | |
| SCHEMBL5105516 | 0.78 | PTGDR2 (0.69) | PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784182-A1 | 2-SULFANYL-BENZIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021418-A1 | 2-SULFANYL-BENZOIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-02 | — | — | WO | disclosed |