Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.85 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.84 |
| ▸ | ATM | Q13315 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113912 | 0.92 | PTGDR2 (1.00) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5120768 | 0.92 | PDPK1 (1.00) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5120963 | 0.88 | PDPK1 (1.00) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5110637 | 0.81 | PDPK1 (0.80) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5113947 | 0.80 | PDPK1 (0.77) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5113955 | 0.78 | PTGDR2 (1.00) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5120470 | 0.78 | PTGDR2 (0.85) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5113732 | 0.77 | ATM (1.00) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5120282 | 0.77 | TP53 (0.82) | PTGDR2PDPK1ATMKMT2AMEN1 | |
| SCHEMBL5107362 | 0.76 | MEN1 (0.92) | PTGDR2PDPK1ATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784182-A1 | 2-SULFANYL-BENZIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2007-05-16 | — | — | EP | claimed |
| WO-2006021418-A1 | 2-SULFANYL-BENZOIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-02 | — | — | WO | claimed |