Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118750 | 1.00 | PTGDR2 (0.67) | PTGDR2MEN1KMT2A | |
| SCHEMBL4133703 | 1.00 | PTGDR2 (0.67) | PTGDR2MEN1KMT2A | |
| SCHEMBL4118749 | 1.00 | PTGDR2 (0.67) | PTGDR2MEN1KMT2A | |
| SCHEMBL14502272 | 0.94 | PTGDR2 (0.71) | PTGDR2MEN1KMT2A | |
| SCHEMBL4128943 | 0.90 | PTGDR2 (0.67) | PTGDR2MEN1KMT2A | |
| SCHEMBL4128940 | 0.90 | PTGDR2 (0.67) | PTGDR2MEN1KMT2A | |
| SCHEMBL4114102 | 0.88 | PTGDR2 (0.85) | PTGDR2MEN1KMT2A | |
| SCHEMBL4127237 | 0.88 | PTGDR2 (0.70) | PTGDR2MEN1KMT2A | |
| SCHEMBL4128335 | 0.88 | PTGDR2 (0.85) | PTGDR2MEN1KMT2A | |
| SCHEMBL5527200 | 0.88 | PTGDR2 (0.70) | PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740547-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100321-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |