Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735559 | 0.86 | MLNR (0.50) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL29395058 | 0.86 | MLNR (0.50) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL30585650 | 0.86 | MLNR (0.50) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL908153 | 0.86 | MLNR (0.50) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL13925775 | 0.86 | MLNR (0.50) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL1737016 | 0.86 | MLNR (0.50) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL8269287 | 0.85 | HPGD (0.53) | HPGDTSHRCNR1MLNRADRB2 | |
| Hydrochloric Acid SCHEMBL3905269 | 0.85 | MLNR (0.49) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL26413056 | 0.81 | MLNR (0.50) | TSHRCNR1MLNRADRB2ADRB1 | |
| SCHEMBL3909221 | 0.74 | MLNR (0.49) | TSHRCNR1MLNRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737847-A2 | NEBIVOLOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS OF NEBIVOLOL | Torrent Pharmaceuticals Ltd (IN) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006025070-A2 | NEBIVOLOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS OF NEBIVOLOL | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-03-09 | — | — | WO | disclosed |