Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181484 | 0.89 | AR (0.68) | ARKCNH2SLC6A4HTR2ASLC22A12 | |
| SCHEMBL4186077 | 0.87 | AR (0.67) | ARKCNH2SLC6A4HTR2ASLC22A12 | |
| SCHEMBL21270043 | 0.80 | AR (0.71) | ARSLC6A4HTR2ASLC22A12 | |
| SCHEMBL5503503 | 0.80 | AR (0.56) | ARKCNH2SLC6A4HTR2ASLC22A12 | |
| SCHEMBL4181443 | 0.77 | AR (0.72) | ARKCNH2SLC6A4HTR2ASLC22A12 | |
| SCHEMBL4182051 | 0.76 | AR (0.59) | ARKCNH2SLC6A4HTR2ASLC22A12 | |
| SCHEMBL4178475 | 0.74 | AR (0.68) | ARKCNH2SLC6A4HTR2ASLC22A12 | |
| SCHEMBL14662245 | 0.74 | AR (0.50) | ARKCNH2SLC22A12CYP3A4CYP2C8 | |
| SCHEMBL4174164 | 0.74 | AR (0.60) | ARKCNH2SLC6A4HTR2ASLC22A12 | |
| SCHEMBL14663667 | 0.74 | AR (0.52) | ARKCNH2SLC22A12CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |