Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.65 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505479 | 1.00 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3120929 | 1.00 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL13752149 | 0.97 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL1913682 | 0.97 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3125520 | 0.97 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL5508812 | 0.97 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3118395 | 0.97 | CACNA2D1 (0.65) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3121991 | 0.89 | CACNA2D1 (0.69) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL3123325 | 0.89 | CACNA2D1 (0.69) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL1913802 | 0.89 | CACNA2D1 (0.69) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840117-A1 | Mono- and disubstituted 3-propyl gamma-aminobutyric acids | Warner-Lambert Company LLC (US) | 2007-10-03 | — | — | EP | disclosed |