Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.64 |
| ▸ | HTR2A | P28223 | 18/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503685 | 0.86 | SLC6A4 (0.65) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5502053 | 0.80 | SLC6A4 (0.66) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5503517 | 0.79 | SLC6A4 (0.64) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5502807 | 0.78 | SLC6A4 (0.69) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5500697 | 0.76 | SLC6A4 (0.57) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5502591 | 0.76 | SLC6A4 (0.60) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL5838723 | 0.74 | HTR2A (0.78) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL5500981 | 0.73 | HTR2A (0.71) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL5501635 | 0.72 | SLC6A4 (0.58) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL6000407 | 0.71 | SLC6A4 (0.52) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791807-A1 | THERAPEUTIC DIPHENYL ETHER LIGANDS | Pfizer Products Incorporated (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006027684-A1 | THERAPEUTIC DIPHENYL ETHER LIGANDS | PFIZER PRODUCTS INC. (US) | 2006-03-16 | — | — | WO | disclosed |