SCHEMBL5505523

SCHEMBL5505523

CC1CCCN1CCCN1[C]N(CCN2CCCC2C)CC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 14/20 0.41
CXCR4 P61073 6/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5506424 1.00 HRH3 (0.41) HRH3CXCR4
SCHEMBL5505798 1.00 HRH3 (0.41) HRH3CXCR4
SCHEMBL5506016 0.97 CXCR4 (0.44) HRH3CXCR4
SCHEMBL5502308 0.97 HRH3 (0.41) HRH3CXCR4
SCHEMBL5505856 0.97 HRH3 (0.41) HRH3CXCR4
SCHEMBL5508033 0.96 HRH3 (0.42) HRH3CXCR4
SCHEMBL5502752 0.93 CXCR4 (0.47) HRH3CXCR4
SCHEMBL5506775 0.93 CXCR4 (0.47) HRH3CXCR4
SCHEMBL5502174 0.91 HRH3 (0.44) HRH3CXCR4
SCHEMBL5500565 0.89 HRH3 (0.38) HRH3CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847530-A1 DIAMINE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-10-24 EP disclosed