Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505635 | 0.91 | F10 (0.45) | F10ARWDR5NPY2RTP53 | |
| SCHEMBL4463968 | 0.87 | F10 (0.53) | F10ARTP53MAPT | |
| SCHEMBL5504077 | 0.82 | F10 (0.42) | F10ARWDR5NPY2RTP53 | |
| SCHEMBL5504066 | 0.82 | F10 (0.46) | F10ARNPY2RTP53MAPT | |
| SCHEMBL4467642 | 0.82 | F10 (0.54) | F10ARTP53MAPT | |
| SCHEMBL5517405 | 0.80 | F10 (0.40) | F10ARWDR5NPY2RTP53 | |
| SCHEMBL5562224 | 0.79 | F10 (0.40) | F10ARWDR5 | |
| SCHEMBL5503712 | 0.79 | F10 (0.38) | F10ARWDR5NPY2RTP53 | |
| SCHEMBL5561433 | 0.78 | F10 (0.48) | F10ARWDR5NPY2RMAPT | |
| SCHEMBL4472368 | 0.78 | F10 (0.59) | F10ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |