Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.62 |
| ▸ | PPARA | Q07869 | 4/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548952 | 0.89 | PPARD (0.71) | PPARDPPARAPPARG | |
| SCHEMBL1600737 | 0.86 | PPARD (0.71) | PPARDPPARAPPARG | |
| SCHEMBL6282731 | 0.85 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL5509214 | 0.83 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL5508820 | 0.81 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL5512008 | 0.80 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4110321 | 0.80 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL3809616 | 0.78 | PPARD (0.65) | PPARDPPARAPPARG | |
| SCHEMBL5508795 | 0.78 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL5512886 | 0.78 | PPARD (0.64) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39916-E1 | Compounds that modulate PPAR activity and methods for their preparation | WARNER LAMBERT COMPANY (US) | 2007-11-06 | — | — | US | disclosed |