⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507678 | 1.00 | — | — | |
| SCHEMBL6920892 | 1.00 | — | — | |
| SCHEMBL5512806 | 0.89 | — | — | |
| SCHEMBL5512797 | 0.89 | — | — | |
| SCHEMBL14533019 | 0.87 | — | — | |
| SCHEMBL5510347 | 0.86 | — | — | |
| SCHEMBL5510358 | 0.86 | — | — | |
| SCHEMBL14533115 | 0.86 | — | — | |
| SCHEMBL5508268 | 0.84 | — | — | |
| SCHEMBL5508276 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214708-B2 | Synthetic discodermolide analogs | KOSAN BIOSCIENCES INCORPORATED (US) | 2007-05-08 | — | — | US | disclosed |
| US-7192980-B2 | Certain substituted polyketides, pharmaceutical compositions containing them and their use in treating tumors | NOVARTIS AG (CH) | 2007-03-20 | — | — | US | disclosed |
| US-6972292-B2 | Certain substituted polyketides, pharmaceutical compositions containing them and their use in treating tumors | NOVARTIS AG (CH) | 2005-12-06 | — | — | US | disclosed |
| US-20050049249-A1 | Certain substituted polyketides, pharmaceutical compositions containing them and their use in treating tumors | KINDER FREDERICK R (US) | 2005-03-03 | — | — | US | disclosed |
| US-20030087934-A1 | Certain substituted polyketides, pharmaceutical compositions containing them and their use in treating tumors | PARALLEL WIRELESS, INC. | 2003-05-08 | — | — | US | disclosed |