Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.63 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014303 | 1.00 | PTGER4 (0.63) | PTGER4PTGER2PTGDR | |
| SCHEMBL27667228 | 0.94 | PTGER4 (0.61) | PTGER4PTGER2PTGDR | |
| SCHEMBL4014889 | 0.94 | PTGER4 (0.61) | PTGER4PTGER2PTGDR | |
| SCHEMBL4017791 | 0.91 | PTGER4 (0.54) | PTGER4PTGER2 | |
| SCHEMBL27673458 | 0.90 | PTGER4 (0.62) | PTGER4PTGER2PTGDR | |
| SCHEMBL4013370 | 0.90 | PTGER4 (0.62) | PTGER4PTGER2PTGDR | |
| SCHEMBL27686217 | 0.87 | PTGER4 (0.61) | PTGER4PTGER2PTGDR | |
| SCHEMBL4020959 | 0.87 | PTGER4 (0.61) | PTGER4PTGER2PTGDR | |
| SCHEMBL27653415 | 0.86 | PTGER4 (0.63) | PTGER4PTGER2PTGDR | |
| SCHEMBL4018028 | 0.86 | PTGER4 (0.63) | PTGER4PTGER2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740211-A2 | COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS AND EP4 RECEPTOR ANTAGONISTS | Pfizer Products Incorporated (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005102389-A2 | COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS AND EP4 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-11-03 | — | — | WO | disclosed |