Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113615 | 0.81 | TLR7 (0.40) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL842243 | 0.81 | PDE4D (0.37) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL2059416 | 0.81 | TLR7 (0.32) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL2059415 | 0.81 | TLR7 (0.32) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| Hydrochloric Acid SCHEMBL2059226 | 0.78 | TLR7 (0.41) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL5119127 | 0.77 | TLR7 (0.40) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL8114799 | 0.77 | TLR7 (0.42) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL2058818 | 0.76 | TLR7 (0.41) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL842373 | 0.74 | TLR7 (0.33) | ADORA2AADORA3ADORA2BADORA1TLR7 | |
| SCHEMBL5457128 | 0.73 | TLR7 (0.38) | TLR7LMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846405-A2 | OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO 4,5-C RING COMPOUNDS AND METHODS | 3M Innovative Properties Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006086634-A2 | OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-17 | — | — | WO | disclosed |