Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881126 | 1.00 | SRC (0.33) | SRC | |
| SCHEMBL3886273 | 0.87 | MELK (0.33) | SRC | |
| SCHEMBL3883355 | 0.86 | SRC (0.33) | SRC | |
| SCHEMBL3887939 | 0.85 | SRC (0.33) | SRC | |
| SCHEMBL3880431 | 0.84 | SRC (0.34) | SRC | |
| SCHEMBL3882415 | 0.84 | SRC (0.33) | SRC | |
| SCHEMBL3882728 | 0.83 | MAP3K8 (0.38) | SRC | |
| SCHEMBL3884442 | 0.83 | MAP3K8 (0.39) | SRC | |
| SCHEMBL3883894 | 0.83 | ENPP1 (0.34) | SRC | |
| SCHEMBL3882246 | 0.82 | MAP4K1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771443-A1 | QUINOLINE THIAZOLINONES WITH CDK1 ANTIPROLIFERATIVE ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006002828-A1 | QUINOLINE THIAZOLINONES WITH CDK1 ANTIPROLIFERATIVE ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2006-01-12 | — | — | WO | disclosed |