SCHEMBL5508971

SCHEMBL5508971

c1ccc(CCCCOCC2CO2)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
TSHR P16473 1/20 0.60
MGLL Q99685 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
ALDH1A1 P00352 1/20 0.50
DRD2 P14416 1/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
HTR2B P41595 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8857213 0.98 MEN1 (0.65) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL8857330 0.98 MEN1 (0.65) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL8857178 0.98 MEN1 (0.65) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL8857231 0.98 MEN1 (0.65) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL8857521 0.95 MEN1 (0.73) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL28106430 0.91 TSHR (0.67) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL2549889 0.88 MEN1 (0.58) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL27926923 0.88 MEN1 (0.58) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL7519513 0.88 MEN1 (0.58) MEN1KMT2ATSHRMGLLTDP1
SCHEMBL13423720 0.87 MEN1 (0.55) MEN1KMT2ATSHRMGLLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105949716-B Epoxy resin composition, prepreg, and fiber-reinforced composite material 三菱化学株式会社 2019-01-04 CN disclosed
CN-105254848-B Epoxy resin composition, prepreg, fiber-reinforced composite material, and method for producing same 三菱化学株式会社 2018-07-24 CN disclosed
CN-103105733-B Photosensitive composition 住友化学株式会社 2017-11-24 CN disclosed
CN-103958560-B Epoxy resin composition, prepreg, fiber-reinforced composite material, and method for producing same MITSUBISHI RAYON CO.,LTD. (JP) 2016-11-30 CN disclosed
CN-103703048-B Curable epoxy resin composition ABB研究有限公司 2016-09-21 CN disclosed
CN-105949716-A EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL 三菱丽阳株式会社 2016-09-21 CN disclosed
CN-103975002-B Prepreg, fiber-reinforced composite material, method for producing same, and epoxy resin composition 三菱丽阳株式会社 2016-07-06 CN disclosed
CN-105254848-A EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR PRODUCING SAME MITSUBISHI RAYON CO 2016-01-20 CN disclosed
CN-103975002-A Prepreg, fiber-reinforced composite material, method for producing same, and epoxy resin composition MITSUBISHI RAYON CO 2014-08-06 CN disclosed
CN-103958560-A Epoxy resin composition, prepreg, fiber-reinforced composite material, and method for producing same MITSUBISHI RAYON CO 2014-07-30 CN disclosed
US-6521667-B1 Calcilytic compounds NPS PHARMACEUTICALS, INC. 2003-02-18 US disclosed
US-6432656-B1 Calcilytic compounds NPS PHARMACEUTICALS, INC. 2002-08-13 US disclosed
US-20020099220-A1 Calcilytic compounds NPS PHARMACEUTICALS, INC. 2002-07-25 US disclosed
US-6022894-A Method of using calcilytic compounds NPS PHARMACEUTICALS, INC. (US) 2000-02-08 US disclosed
CN-1221401-A Calcilytic compounds NPS PHARMA INC (US) 1999-06-30 CN disclosed
EP-0901459-A1 CALCILYTIC COMPOUNDS NPS PHARMACEUTICALS, INC. (US) 1999-03-17 EP disclosed
US-5688823-A ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS SANKYO COMPANY, LIMITED (JP) 1997-11-18 US disclosed
WO-1997037967-A1 CALCILYTIC COMPOUNDS NPS PHARMACEUTICALS, INC. (US) 1997-10-16 WO disclosed
US-5578620-A TREATMENT OF DIABETES AND HYPERLIPEMIA SANKYO COMPANY, LIMITED (JP) 1996-11-26 US disclosed
EP-0678511-A2 Thiazolidine and oxazolidine derivatives, their preparation and their medical use SANKYO COMPANY LIMITED (JP) 1995-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099220-A1 Calcilytic compounds CALCR, CASR, CALCRL MEN1 337/4885KMT2A 4810/4885TSHR 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.