Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506296 | 0.98 | TRPV1 (0.42) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL5503566 | 0.93 | F10 (0.42) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL5499138 | 0.93 | F10 (0.41) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL5502075 | 0.93 | F10 (0.42) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL5527807 | 0.91 | TRPV1 (0.41) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL5509410 | 0.89 | F10 (0.47) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL5526021 | 0.89 | TRPV1 (0.39) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL4467392 | 0.88 | F10 (0.51) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL5506981 | 0.88 | F10 (0.47) | FAAHTRPV1F10SMN1; SMN2LMNA | |
| SCHEMBL4477339 | 0.86 | F10 (0.51) | F10SMN1; SMN2LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |