Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.34 |
| ▸ | HTR2B | P41595 | 7/20 | 0.34 |
| ▸ | HTR1A | P08908 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518086 | 0.81 | KCNH2 (0.49) | KCNH2SLC2A1 | |
| SCHEMBL5506820 | 0.76 | KCNH2 (0.37) | KCNH2SLC2A1 | |
| SCHEMBL3781930 | 0.73 | SLC2A1 (0.52) | KCNH2SLC2A1DRD2HTR2BHTR1A | |
| SCHEMBL4495706 | 0.70 | KCNH2 (0.47) | KCNH2SLC2A1 | |
| SCHEMBL5516460 | 0.69 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL13921369 | 0.68 | KCNH2 (0.81) | KCNH2SLC2A1 | |
| SCHEMBL4489210 | 0.68 | SLC2A1 (0.51) | KCNH2SLC2A1 | |
| SCHEMBL5435565 | 0.68 | KCNH2 (0.40) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL6271264 | 0.68 | KCNH2 (0.80) | KCNH2SLC2A1 | |
| SCHEMBL5436003 | 0.67 | KCNH2 (0.48) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | claimed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | claimed |